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To control for SES as a potential confounding factor without considering underlying relationships may lead to incorrect risk estimates

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That's why nicotine is not included in most panel drug tests

However, one animal study has demonstrated that e-cigarette vapours can cause DNA changes in rat models which is the mechanism through which cancer develops. And even though the main cancer-causing chemicals (like tar) of tobacco smoke are absent in e-cigarettes, many other carcinogenic particles are still present

An impaired sense of smell can also be dangerous

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